Table 2.

Comparison of MDA, paraoxonase, and arylesterase levels in the patients taking each treatment

	Typical antipsychotics (n=11)	Atypical antipsychotics (n=19)	Combined antipsychotics (n=11)	Healthy controls (n=43)	Comparison	p value
MDA (nmol/mL)	6.6±3.4	4.5±1.7	5.6±3.0	3.9±1.8	1–4	0.001
					2–4	NS
					3–4	NS
Paraoxonase (U/L)	67.8±4.1	68.7±3.4	69.1±4.4	66.9±5.2	1–4	NS
					2–4	NS
					3–4	NS
Arylesterase (U/L)	131.0±22.4	138.1±24.3	133.0±26.3	114.5±24.9	1–4	NS
					2–4	0.005
					3–4	NS

Values are presented as mean±standard deviation.

MDA, malondialdehyde; PON1, paraoxonase; ARY, arylesterase; NS, not significant.

ARY levels were significantly increased only in patients using atypical antipsychotics p=0.005. MDA was significantly increased in patients on typical antipsychotic medication, p=0.001. Other comparisons between groups were statistically not significant (all p values were above 0.05).