Table 2.
HF-EFA fed rats experience alterations in plasma one carbon metabolite profile, while plasma lipids remain unchanged, compared to HF-AFA fed rats.
| HF-AFA | HF-EFA | |
|---|---|---|
| Plasma one carbon metabolites | ||
| Folate (nmol/L) | 41.56 ± 0.50 | 41.30 ± 0.72 |
| Homocysteine (μM) | 3.28 ± 0.17 | 2.650 ± 0.14 * |
| Methionine (μM) | 69.73 ± 2.93 | 62.58 ± 1.01 * |
| Dimethylglycine (μM) | 13.10 ± 0.98 | 15.68 ± 0.95 |
| Methylglycine (μM) | 7.19 ± 0.48 | 6.21 ± 0.31 |
| Glycine (μM) | 425.0 ± 21.6 | 345.5 ± 24.0 * |
| Serine (μM) | 339.2 ± 11.2 | 364.5 ± 10.9 |
| Cystathionine (nM) | 914.7 ± 69.2 | 763.3 ± 37.2 |
| Cysteine (nM) | 311.3 ± 4.5 | 305.7 ± 9.7 |
| α-aminobutyrate (μM) | 27.68 ± 2.6 | 35.60 ± 4.0 |
| Plasma lipids | ||
| Triglyceride (µg/mL) | 292.6 ± 43.26 | 211.8 ±46.21 |
| Cholesterol Ester (µg/mL) | 72.92 ± 5.87 | 60.18 ± 7.97 |
| Free Cholesterol (µg/mL) | 134.4 ± 18.65 | 118.1 ± 15.41 |
Values are means ± SEM, * p < 0.05.