Table 2.

Selenium level in the blood, liver and prostate of rats following zinc gluconate (Zn), sodium selenite (Se) and selenomethionine (SeMet) administration given jointly or separately for 30, 60 and 90 days and then after 90 and 180 days post administration.

	Blood (μg/mL)	Liver (μg/g w.t.)	Prostate (μg/g w.t.)
			V Lobe	DL Lobe
Administration Period
30-day
Control	0.51 ± 0.03	1.18 ± 0.02	0.41 ± 0.05	0.23 ± 0.03
Zn	0.53 ± 0.02	1.17 ± 0.07	0.37 ± 0.05	0.28 ± 0.06
Se	0.56 ± 0.03	1.24 ± 0.02 *	0.40 ± 0.08	0.30 ± 0.03 *
SeMet	0.56 ± 0.03	1.27 ± 0.03 *	0.52 ± 0.05 *	0.31 ± 0.02 *
Zn + Se	0.52 ± 0.04	1.24 ± 0.05 *	0.41 ± 0.04	0.32 ± 0.02 *
Zn + SeMet	0.50 ± 0.02	1.26 ± 0.05 *	0.51 ± 0.05 *	0.31 ± 0.02 *
60-day
Control	0.53 ± 0.02	1.22 ± 0.02	0.41 ± 0.07	0.24 ± 0.04
Zn	0.51 ± 0.02	1.28 ± 0.09	0.42 ± 0.04	0.27 ± 0.02
Se	0.58 ± 0.02 *	1.41 ± 0.09 *	0.48 ± 0.06	0.36 ± 0.06 *
SeMet	0.56 ± 0.01 *	1.40 ± 0.12 *	0.63 ± 0.08 *	0.38 ± 0.04 *
Zn + Se	0.55 ± 0.02	1.31 ± 0.06 *	0.50 ± 0.06	0.34 ± 0.05 *
Zn + SeMet	0.52 ± 0.03	1.31 ± 0.06 *	0.62 ± 0.07 *	0.36 ± 0.04 *
90-day
Control	0.51 ± 0.03	1.21 ± 0.08	0.45 ± 0.07	0.28 ± 0.02
Zn	0.52 ± 0.02	1.27 ± 0.09	0.49 ± 0.05	0.27 ± 0.03
Se	0.59 ± 0.03 *	1.41 ± 0.04 *	0.49 ± 0.04	0.42 ± 0.04 *
SeMet	0.58 ± 0.03 *	1.39 ± 0.04 *	0.69 ± 0.09 *	0.39 ± 0.02 *
Zn + Se	0.51 ± 0.04	1.36 ± 0.05 *	0.52 ± 0.04	0.37 ± 0.07 *
Zn + SeMet	0.50 ± 0.04	1.41 ± 0.06 *	0.62 ± 0.05 *	0.39 ± 0.06 *
Post Administration Period
90-day
Control	0.51 ± 0.03	1.13 ± 0.10	0.36 ± 0.04	0.26 ± 0.03
Zn	0.52 ± 0.02	1.20 ± 0.07	0.36 ± 0.07	0.27 ± 0.02
Se	0.52 ± 0.02	1.24 ± 0.02 *	0.30 ± 0.03	0.32 ± 0.02 *
SeMet	0.56 ± 0.03	1.37 ± 0.12 *	0.39 ± 0.03	0.31 ± 0.01 *
Zn + Se	0.50 ± 0.02	1.24 ± 0.08 *	0.44 ± 0.05	0.33 ± 0.04 *
Zn + SeMet	0.55 ± 0.04	1.24 ± 0.07 *	0.42 ± 0.07	0.37 ± 0.05 *
180-day
Control	0.51 ± 0.04	1.09 ± 0.09	0.30 ± 0.02	0.26 ± 0.02
Zn	0.51 ± 0.02	1.18 ± 0.05	0.32 ± 0.05	0.30 ± 0.03
Se	0.50 ± 0.02	1.26 ± 0.08	0.38 ± 0.08	0.33 ± 0.04 *
SeMet	0.54 ± 0.05	1.21 ± 0.05	0.32 ± 0.03	0.30 ± 0.01 *
Zn + Se	0.50 ± 0.03	1.09 ± 0.08	0.31 ± 0.08	0.31 ± 0.03 *
Zn + SeMet	0.55 ± 0.05	1.27 ± 0.13	0.31 ± 0.07	0.36 ± 0.04 *

All values are expressed as means ± SD; * Results statistically significant compared to controls, p ≤ 0.05.