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. 2016 Oct 4;8(10):601. doi: 10.3390/nu8100601

Table 3.

Selected biochemical parameters in rats following zinc gluconate (Zn), sodium selenite (Se) and selenomethionine (SeMet) administration given jointly or separately for 30, 60 and 90 days and then after 90 and 180 days post-administration.

TAS (mM/L Plasma) ESOD (U/g Hb) GPx (U/g Hb)
Administration Period
30-day
Control 1.07 ± 0.13 3282.5 ± 423.6 21.85 ± 1.34
Zn 1.13 ± 0.14 3690.0 ± 440.3 21.79 ± 2.37
Se 1.20 ± 0.16 3614.0 ± 164.8 24.18 ± 2.33
SeMet 1.06 ± 0.20 3384.0 ± 262.3 22.03 ± 1.12
Zn + Se 1.16 ± 0.16 3614.0 ± 589.2 22.61 ± 1.39
Zn + SeMet 1.16 ± 0.15 3512.0 ± 234.0 21.89 ± 1.54
60-day
Control 1.06 ± 0.09 3393.4 ± 388.8 21.89 ± 1.88
Zn 1.06 ± 0.10 3802.5 ± 393.3 21.98 ± 2.21
Se 1.01 ± 0.06 3420.0 ± 191.1 24.81 ± 1.94
SeMet 1.02 ± 0.07 3280.0 ± 362.2 23.05 ± 2.59
Zn + Se 0.99 ± 0.11 3724.1 ± 423.1 23.22 ± 1.99
Zn + SeMet 0.96 ± 0.09 3632.2 ± 352.3 22.33 ± 2.19
90-day
Control 0.99 ± 0.03 3803.3 ± 192.9 21.64 ± 1.70
Zn 0.95 ± 0.11 4220.0 ± 624.1 22.94 ± 3.00
Se 0.90 ± 0.10 3470.0 ± 435.6 25.35 ± 4.53
SeMet 0.99 ± 0.12 3520.0 ± 449.2 22.65 ± 2.89
Zn + Se 0.91 ± 0.07 3970.0 ± 701.2 23.11 ± 2.96
Zn + SeMet 0.94 ± 0.05 3828.0 ± 877.7 21.83 ± 1.31
Post Administration Period
90-day
Control 0.76 ± 0.03 3230.0 ± 372.4 20.62 ± 1.58
Zn 076 ± 0.08 3542.5 ± 352.8 21.75 ± 1.51
Se 0.76 ± 0.09 3438.0 ± 222.1 24.31 ± 2.49
SeMet 0.83 ± 0.05 3102.0 ± 368.8 21.32 ± 1.56
Zn + Se 0.77 ± 0.10 3530.0 ± 593.5 21.38 ± 1.47
Zn + SeMet 0.73 ± 0.15 3556.0 ± 421.0 20.83 ± 1.70
180-day
Control 0.74 ± 0.07 3443.1 ± 325.6 20.68 ± 2.09
Zn 0.91 ± 0.11 3802.0 ± 419.7 20.02 ± 1.33
Se 0.89 ± 0.09 3490.0 ± 310.4 22.37 ± 1.78
SeMet 0.89 ± 0.10 3676.2 ± 290.0 20.68 ± 1.03
Zn + Se 0.91 ± 0.10 3381.0 ± 361.9 21.93 ± 1.57
Zn + SeMet 0.89 ± 0.16 3880.2 ± 411.1 20.39 ± 1.79

All values are expressed as means ± SD.