Table 2.
Comparison of target organ damage in patients with or without hyperhomocysteinemia.
| Total | Normohomocysteinemia | Hyperhomocysteinemia | p Value | |
|---|---|---|---|---|
| (N = 1042) | (N = 492) | (N = 550) | ||
| eGFR-MDRD (mL/min/1.73 m2) | 38.12 (8.52–90.08) | 87.68 (49.22–119.84) | 11.63 (5.52–35.56) | <0.001 |
| LVMI (g/m2) | 124.68 ± 37.35 | 116.19 ± 39.92 | 128.99 ± 35.26 | <0.001 |
| E/A | 1.11 ± 0.45 | 1.20 ± 0.43 | 1.02 ± 0.45 | <0.001 |
| cIMT (mm) | 0.75 ± 0.34 | 0.71 ± 0.31 | 0.78 ± 0.35 | <0.05 |
cIMT: Carotid intima-media thickness; eGFR: Estimated glomerular filtration rate; LVMI: Left ventricular mass index; E/A: Peak velocities of early (E) and late (A) trans-mitral flow and deceleration time; MDRD: Modification of Diet in Renal Disease.