Table 6.
Crude and adjusted hazard ratios of mortality and renal replacement therapy start, by diabetes, Charlson index, proteinuria, and GFR (Cox analysis).
| MORTALITY | |||||
|---|---|---|---|---|---|
| n/N | Crude RR (95% CIs) | p Value | Adjusted HR (95% CIs) | p Value | |
| Diabetes | 52/149 | 1.4534 | <0.0001 | 1.146 | 0.5173 |
| No-Diabetes | 51/300 | (1.1831–1.7855) | (0.758–1.733) | ||
| Charlson index | <0.0001 | <0.0001 | |||
| <7 | 14/203 | 4.0188 | 5.155 | ||
| ≥7 | 89/246 | (2.4465–6.6014) | (2.851–9.320) | ||
| Proteinuria (g/day) | <0.0001 | 0.0615 | |||
| <1 | 74/247 | 0.6959 | 0.654 | ||
| ≥1 | 29/202 | (0.5928–0.8170) | (0.419–1.021) | ||
| GFR (mL/m) | 0.1065 | 0.0928 | |||
| <30 | 85/344 | 0.9071 | 0.644 | ||
| ≥30 | 18/105 | (0.8144–1.0104) | (0.385–1.076) | ||
| RRT START | |||||
| n/N | Crude RR (95% CIs) | p Value | Adjusted HR (95% CIs) | p Value | |
| Diabetes | 32/149 | 0.9658 | 0.6584 | 0.781 | 0.3175 |
| No-diabetes | 70/300 | (0.8303–1.1234) | (0.481–1.268) | ||
| Charlson index | 0.0138 | 0.1098 | |||
| <7 | 57/246 | 0.7529 | 0.692 | ||
| ≥7 | 45/203 | (0.6090–0.9308) | (0.441–1.087) | ||
| Proteinuria (g/day) | <0.0001 | <0.0001 | |||
| <1 | 34/247 | 1.8415 | 3.703 | ||
| ≥1 | 68/202 | (1.3823–2.4533) | (2.409–5.691) | ||
| GFR (mL/m) | <0.0001 | <0.0001 | |||
| <30 | 96/344 | 0.7594 | 0.115 | ||
| ≥30 | 6/105 | (0.6994–0.8245) | (0.005–0.267) | ||
Legend: GFR: Glomerular filtration rate (EPI formula); RR: Relative risk; HR: Hazard ratio. RRT: Renal replacement therapy.