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. 2016 Sep 14;2(10):687–701. doi: 10.1021/acscentsci.6b00086

Table 2. Liver and Blood Stage Potencies for Selected Compounds.

OSM-S- P. berghei IC50 (nM) cytotoxicity (HepG2, IC50, nM) blood stage potency (3D7, nM)
5a,b 24000, 14000 9800, 18000 502c
38a,b 19, 13 >50000 79d
111e 350 4400 147d
c

See Table SB1.

d

See Table SB3.

e

Data Set S29; Figure S31, liver stage potency curve.