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. Author manuscript; available in PMC: 2016 Oct 28.
Published in final edited form as: Eur J Clin Microbiol Infect Dis. 2015 Jan 13;34(5):963–974. doi: 10.1007/s10096-014-2309-2

Figure 3. Transcriptional response of genes in the FAP-IFIH1-GCA-KCNH7 LD region to various microbial stimuli.

Figure 3

Figure 3

(A) Peripheral blood mononuclear cells (PBMCs) from healthy volunteers were stimulated for either 4 or 24 hours with Borrelia burgdorferi, Candida albicans, Escherichia coli-derived lipopolysaccharide (LPS), or Mycobacterium tuberculosis (MTB). Gene expression was measured using microarrays and normalized to the control RPMI condition (untreated). (B) Gene expression (Mean ± SD) in PBMCs of healthy controls (n=3) and patients suffering from chronic mucocutaneous candidiasis (CMC) (n=2) were stimulated with C. albicans for 4 hours. P values were calculated using the Welch-corrected t test.