Table 1.
Effect of H9N2 avian influenza virus (AIV) and mesenchymal stromal cells (MSCs) on arterial blood gas analysis of mice
| Groups | pH | PO2 (mmHg) | PCO2 (mmHg) | SO2 |
|---|---|---|---|---|
| A: Control (allantoic fluid; n = 10) | 7.23 ± 0.032 | 90.8 ± 6.43 | 38.5 ± 1.66 | 92.7 ± 0.73 |
| B: MSCs (1 × 105 MSCs; n = 10) | 7.29 ± 0.031 | 88.2 ± 5.51 | 37.9 ± 1.11 | 93.8 ± 1.02 |
| C: H9N2-infected mice (1 × 104 MID50 H9N2AIV; n = 15) | 6.62 ± 0.286 | 46 ± 4.17* | 65.34 ± 2.55* | 64.82 ± 1.63* |
| D: H9N2-infected mice + MSCs (1 × 104 MID50 H9N2AIV + 1 × 105 McCoy; n = 15) | 6.71 ± 0.257 | 48.2 ± 5.11* | 64.32 ± 1.98* | 68.15 ± 1.75* |
| E: H9N2-infected mice + MSCs (1 × 104 MID50 H9N2AIV + 1 × 105 MSCs; n = 15, 30 min following infection) | 6.84 ± 0.613 | 68 ± 5.76*▲ | 50.05 ± 1.09*▲ | 78.47 ± 1.54*▲ |
| F: H9N2-infected mice (1 × 104 MID50 H9N2AIV; n = 15) | 6.97 ± 0.375 | 46 ± 4.35* | 66 ± 3.34* | 65 ± 2.44* |
| G: H9N2-infected mice + MSCs (1 × 104 MID50 H9N2AIV + 1 × 105 MSCs; n = 15, 1 day following infection) | 6.77 ± 0.712 | 60 ± 3.35*▲ | 52.39 ± 4.13*▲ | 75.89 ± 2.44*▲ |
*Response that is significantly different from the control (p < 0.05)
▲Response that is significantly different from the H9N2-infected mice (p < 0.05)
PaCO 2 partial pressure of arterial carbon dioxide, PaO 2 partial pressure of arterial oxygen, SaO 2 saturation of arterial oxygen