Table 5.
Technique | Location | Measurement | Age < 14 | Age > 14 | |||
Average | SD | Average | SD | p | |||
MOLLI | Septal | Native T1 | 1054.69 | 32.04 | 1040.40 | 73.98 | 0.20 |
Septal | ECVa | 27.57 | 4.40 | 28.04 | 6.49 | 0.67 | |
SASHA | Septal | Native T1 | 1257.36 | 43.68 | 1217.37 | 74.60 | <0.01 |
Septal | ECVa | 23.74 | 2.43 | 23.44 | 5.23 | 0.71 | |
LVEF b > 55 % | LVEF b < 55 % | ||||||
Average | SD | Average | SD | p | |||
MOLLI | Septal | Native T1 | 1040.32 | 37.79 | 1055.49 | 85.86 | 0.32 |
Septal | ECVa | 26.81 | 4.13 | 29.40 | 7.39 | 0.06 | |
SASHA | Septal | Native T1 | 1230.34 | 58.48 | 1238.84 | 78.02 | 0.58 |
Septal | ECVa | 22.64 | 2.78 | 24.99 | 5.70 | 0.02 | |
LGE c - | LGE c + | ||||||
Average | SD | Average | SD | p | |||
MOLLI | Septal | Native T1 | 1039.49 | 39.62 | 1050.62 | 71.69 | 0.33 |
Septal | ECVa | 27.09 | 3.84 | 28.36 | 6.68 | 0.24 | |
SASHA | Septal | Native T1 | 1223.85 | 55.55 | 1240.30 | 72.79 | 0.22 |
Septal | ECVa | 23.06 | 2.93 | 23.89 | 5.03 | 0.31 |
Septal values of native T1 and ECV using the MOLLI and SASHA techniques for measuring T1 within subgroups of the DMD cohort divided into those < 14 years (n = 12), and those > 14 years (n = 8); divided again into those with LVEF > 55 % (n = 12) and LVEF < 55 % (n = 8); divided again into those with LGE (n = 8) and those without LGE (n = 12). There are few significant differences between the group, including only septal ECV using MOLLI and SASHA when the group is divided by LVEF, and native T1 when the group is divided by age.a ECV extracellular volume fraction, bLVEF left ventricular ejection fraction, cLGE late gadolinium enhancement