Table 1.
Clinicopathologic Variable | Training Cohort | Validation Cohort | ||||||
---|---|---|---|---|---|---|---|---|
Total | TRIM62 expression | P-value | Total | TRIM62 expression | P-value | |||
low | High | low | High | |||||
Age(years) | ||||||||
≦42 | 61 | 40 | 21 | 0.388 | 44 | 26 | 18 | 0.973 |
> 42 | 47 | 27 | 20 | 37 | 22 | 15 | ||
FIGO stage | ||||||||
Ia2 | 9 | 2 | 7 | 0.063 | 11 | 2 | 9 | 0.007 a |
Ib1 | 56 | 34 | 22 | 39 | 22 | 17 | ||
Ib2 | 18 | 12 | 6 | 14 | 9 | 5 | ||
IIa1 | 12 | 8 | 4 | 7 | 6 | 1 | ||
IIa2 | 13 | 11 | 2 | 10 | 9 | 1 | ||
Tumor size(cm) | ||||||||
≦4 | 74 | 41 | 33 | 0.036 | 54 | 27 | 27 | 0.016 |
> 4 | 34 | 26 | 8 | 27 | 21 | 6 | ||
Pathologic types | ||||||||
Squamous cell carcinoma | 68 | 43 | 25 | 0.738 | 53 | 30 | 23 | 0.503 |
Adenocarcinoma | 40 | 24 | 16 | 28 | 18 | 10 | ||
Differentiation grade | ||||||||
Well | 9 | 4 | 5 | 0.081 | 7 | 3 | 4 | 0.046 a |
Moderate | 48 | 26 | 22 | 36 | 17 | 19 | ||
Poor | 51 | 37 | 14 | 38 | 28 | 10 | ||
Stromal invasion | ||||||||
< 1/2 | 61 | 30 | 31 | 0.004 | 50 | 25 | 25 | 0.031 |
≧1/2 | 47 | 36 | 11 | 31 | 23 | 8 | ||
Lymphovascular space invasion | ||||||||
Yes | 14 | 12 | 2 | 0.050 | 11 | 8 | 3 | 0.511a |
No | 94 | 55 | 39 | 70 | 40 | 30 | ||
Pelvic-lymph node metastasis | ||||||||
Yes | 18 | 15 | 3 | 0.041 | 14 | 11 | 3 | 0.106 |
No | 90 | 52 | 38 | 67 | 37 | 30 | ||
Vaginal involvement | ||||||||
Yes | 4 | 4 | 0 | 0.295a | 3 | 3 | 0 | 0.267a |
No | 104 | 63 | 41 | 78 | 45 | 33 | ||
Parametrial infiltration | ||||||||
Yes | 3 | 3 | 0 | 0.287a | 2 | 2 | 0 | 0.511a |
No | 105 | 64 | 41 | 79 | 46 | 33 | ||
Recurrence | ||||||||
Yes | 24 | 22 | 2 | 0.001 | 20 | 18 | 2 | 0.001 |
No | 84 | 45 | 39 | 61 | 30 | 31 | ||
Vital status at follow-up | ||||||||
Alive | 86 | 47 | 39 | 0.002 | 61 | 30 | 31 | 0.001 |
Dead | 22 | 20 | 2 | 20 | 18 | 2 |
Abbreviations: FIGO the International Federation of Gynecology and Obstetrics
a P-value from Fisher’s exact test; The bold number inside the table reflected P < 0.05