Table 3.

Univariate and Multivariate Analysis of Factors Associated with Overall Survival and Disease-Free Survival in Validation Cohort

Clinicopathologic Variable	Total	OS			DFS
		Univariate	Multivariate Analysis		Univariate	Multivariate Analysis
		P	RR (95 % CI)	P	P	RR (95 % CI)	P
Age(years)
≦42	44
> 42	37	0.682	n.a.	n.a.	0.726	n.a.	n.a.
FIGO stage
Ia2	11		1			1
Ib1	39
Ib2	14
IIa1	7
IIa2	10	<0.001	1.546(1.082–2.211)	0.017	<0.001	1.575(1.102–2.250)	0.013
Tumor size(cm)
≦4	54
> 4	27	0.191	n.a.	n.a.	0.210	n.a.	n.a.
Pathologic types
Squamous cell carcinoma	53
Adenocarcinoma	28	0.933	n.a.	n.a.	0.908	n.a.	n.a.
Differentiation grade
Well	7
Moderate	36
Poor	38	0.105	n.a.	n.a.	0.115	n.a.	n.a.
Stromal invasion
< 1/2	50		1			1
≧1/2	31	0.020	1.900(0.763–4.734)	0.168	0.024	1.819(0.735–4.502)	0.196
Lymphovascular space invasion
Yes	11
No	70	0.122	n.a.	n.a.	0.182	n.a.	n.a.
Pelvic-lymph node metastasis
Yes	14		1			1
No	67	0.016	2.098(0.821–5.358)	0.122	0.026	1.775(0.697–4.518)	0.229
Vaginal involvement
Yes	3
No	78	0.769	n.a.	n.a.	0.662	n.a.	n.a.
Parametrial infiltration
Yes	2
No	79	0.218	n.a.	n.a.	0.316	n.a.	n.a.
TRIM62
low	48		1			1
high	33	0.006	0.209(0.048–0.917)	0.038	0.006	0.206(0.047–0.902)	0.036

Abbreviations: n.a. Not application, FIGO the International Federation of Gynecology and Obstetrics; The bold number inside the table reflected P < 0.05