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. 2016 Oct 24;215(2):231–243. doi: 10.1083/jcb.201602001

Table 1. Genes induced by nuclear calcium signaling (i.e., down-regulated by CaMBP4) with a role in T cell activation.

Signaling MAPKs pathway Transcription
PRKCQ (PKCθ) MAP4K2 STAT2
PLCG2 (PLCγ2) RASGRP3 SMAD3
Receptors IFN signaling SMAD4
CD27 IFITM SMAD7
CD8A IRF8 FOXO1
IL-2R IFI27 EOMES
TGFβ R IRFI35
Cytokines Inflammation and cytotoxic activity Adhesion molecules
IFNγ KLRD1 (CD94) ITGB2
IL-2 KLRB1 ITGAL
IL-3 GZMA (granzyme) ICAM3
IL-4 GZMK (granzyme) ITGB7
GM-CSF (CSF2) GZMH (granzyme) Rho GTPase signaling
TNFSF13B (BAFF) PTGER2 RAP-GEF
TNFSF10 ARHGAP4