Table 2. Genes repressed by nuclear calcium signaling (i.e., up-regulated by CaMBP4) with a function in promoting anergy.
Signaling | Inhibitors of MAPKs pathway | E3 ubiquitin ligases | Proteasome |
---|---|---|---|
Fas | PTPN7 | RNF19B | PSMA6 |
CD97 | PTPN22 | CBL | PSMA1 |
GDI1 | PTPN6 | Transcription | PSMC6 |
RGS16 | DUSP6 | NFATC1 | PSMD12 |
GEM | DUSP5 | EGR1 | PSMD6 |
Sh2D2A | DUSP2 | EGR2 | PSMB2 |
Receptors | DUSP8 | EGR3 | PSMC1 |
FasL | DUSP1 | STAT4 | PSMC4 |
CD44 | DUSP4 | STAT6 | PSMA3 |
IL7R | DGKα | Jarid2 | Other functions |
TNFRSF4 | Inhibitors of proliferation | Nr4a2 | Actn4 |
ICOS-LG | BTG2 | Nr4a3 | CCRN4L |
Inhibitory receptors | IER5 | IRF4 | Hif1a |
PDCD1 (PD1) | CDKN1A (P21) | Zfp36 | S100a |
CTLA4 | GADD45B | Stx11 | |
PFN1 | |||
CDKN1B (p27 kip) |