Table 4.

Analysis of covariance adjusted means and multiple comparisons for sensory nerve action potential transformed into the square root of the values (SNAPsqrt) according to Common Terminology Criteria for Adverse Events (CTCAE)

CTCAE	SNAPsqrt
	Unadjusted		Adjusted		n
	Mean	SD	Mean	SE
Grade 1	2.85	0.61	2.88	0.13	21
Grade 2	2.25	0.60	2.13	0.15	18
Grade 3	1.39	0.75	1.52	0.19	11
Comparison	Mean difference	SE	Bonferroni adjusted 95% CI		P‐value
Grade 1 vs grade 2	0.75*	0.20	0.26, 1.24		0.001*
Grade 1 vs grade 3	1.36*	0.22	0.80, 1.20		<0.001*
Grade 2 vs grade 3	0.61*	0.24	0.01, 1.22		0.047*

*P < 0.05, where P‐values are adjusted using the Bonferroni correction. CI, confidence interval. R ² = 0.53, adjusted R ² = 0.50, adjustments based on age = 62.08. Homogeneity of regression tested and not significant: F = 0.83, P > 0.05. Age regression coefficient = −0.022, P = 0.006.