Table 6.
Relationships between YAP1 expression levels and clinicopathological factors in 71 high‐grade neuroendocrine tumors
| YAP1 expression | P‐value | ||
|---|---|---|---|
| Positive | Negative | ||
| Pathological stage† | |||
| Stage I | 7 | 25 | >0.9999 |
| Stages II–IV | 5 | 21 | |
| T‐stage‡ | |||
| T1 | 5 | 22 | >0.9999 |
| T2, T3, T4 | 8 | 35 | |
| Nodal involvement§ | |||
| Positive | 2 | 19 | 0.1817 |
| Negative | 10 | 28 | |
| Lymphatic invasion¶ | |||
| Positive | 2 | 31 | 0.1239 |
| Negative | 6 | 21 | |
| Vessel invasion†† | |||
| Positive | 7 | 40 | >0.9999 |
| Negative | 1 | 11 | |
| Pleural invasion‡‡ | |||
| Positive | 10 | 26 | 0.0658 |
| Negative | 3 | 30 | |
| Tumor size, cm§§ | |||
| <3 | 7 | 36 | 0.5351 |
| ≥3 | 6 | 20 | |
| Pulmonary metastasis¶¶ | |||
| Positive | 1 | 3 | 0.5751 |
| Negative | 12 | 53 | |
| Age, years | |||
| <60 | 1 | 8 | >0.9999 |
| ≥60 | 12 | 50 | |
| Sex | |||
| Male | 9 | 55 | 0.0183 |
| Female | 4 | 3 | |
†Stages (I or II–IV) of 13 cases were unknown. ‡Pathological T‐stage of one case was unknown. §Presence or absence of nodal involvement in 12 cases was unknown. ¶Presence or absence of lymphatic invasion in 11 cases was unknown. ††Presence or absence of vessel invasion in 11 cases was unknown. ‡‡Presence or absence of pleural invasion in two cases was unknown. §§Tumor sizes of two cases were unknown. ¶¶Presence or absence of pulmonary metastasis in two cases was unknown. Underlined P‐values are considered significant (P < 0.05).