Table 1.
Genes expressed in a Myd88-dependent manner in 4T1 cells.
| aconsMydlow | bindMydlow | cRELEVANT ASSOCIATED FUNCTION(S) | REFS | |
|---|---|---|---|---|
| Krt14 | −6.76 | −8.26 | Associated with a migratory phenotype in breast cancer. | 55 |
| Dnajc6 | −6.28 | −7.56 | Associated with progression of hepatocellular carcinoma. | 27 |
| Adra2a | −3.27 | −4.32 | Associated with breast cancer proliferation and tumor growth. | 12 |
| Fam83c | −2.48 | −3.88 | Associated with mammary epithelial cell transformation. | 56 |
| Vipr1 | −2.50 | −3.14 | Expressed by breast cancer. | 63 |
| Cdh3 | −8.87 | −2.07 | Associated with breast cancer invasion and metastasis. | 11 |
| Slco5a1 | −2.08 | −7.31 | Associated with the uptake of hormones during breast cancer development. | 57 |
| Fgd5 | −2.29 | −3.92 | Amplified in breast cancer and associated with cell proliferation. | 23 |
| Rab3b | −3.55 | −2.09 | Associated with breast cancer proliferation and invasion. | 24 |
| Folr1 | −2.04 | −3.31 | Expressed by double and triple negative breast cancers and associated with poor outcome for patients with breast cancer. | 13 |
| Aldh1a3 | −2.05 | −3.33 | Correlated with tumor stage for patients with triple negative breast cancer. | 14 |
| Ccdc170 | −2.24 | −2.64 | Associated with genetic rearrangements in ER+ breast cancer. | 64 |
| Lgals4 | −2.66 | −2.13 | Considered an angiogenesis and metastasis factor. | 21 |
| Anxa8 | −2.59 | −2.13 | Predicts poor survival for patients with breast cancer. | 25 |
| Tspyl5 | −2.18 | −2.12 | Predictor of poor outcome in patients with breast cancer. | 26 |
| Vldlr | −2.07 | −2.85 | Associated with metastasis in breast cancer. | 22 |
| Ppp1r16b | −2.02 | −2.39 | Contributes to angiogenesis by decreasing PTEN. | 65 |
Notes:
a
Relative downregulation of genes in consMydlow cells relative to control.
b
Relative downregulation of genes in indMydlow cells relative to control.
c
Select functions that have been attributed to the downregulated genes.