Table 3.
Additional genes influenced by Myd88-dependent signaling in 4T1 cells.
| aconsMydlow | bindMydlow | cRELEVANT ASSOCIATED FUNCTION(S) | REFS | |
|---|---|---|---|---|
| Ptn | 3.33 | 22.17 | May contribute to angiogenesis in breast cancer. | 39 |
| Tslp | 15.61 | 3.10 | Correlated with growth and metastasis of 4T1 tumors. | 40 |
| Mmp13 | 3.55 | 2.45 | Associated with breast cancer invasion and metastasis. | 41 |
| Il1b | 8.27 | 2.20 | Associated with breast cancer progression. | 18 |
| Fos | 2.55 | 2.10 | May contribute to tumor growth. | 42 |
| Mmp9 | 2.99 | 2.07 | Associated with breast cancer metastasis. | 17 |
| Hsd17b7 | 2.06 | 2.15 | Associated with estradiol synthesis in breast cancer. | 43 |
| Psd3 | −15.15 | −2.81 | Breast cancer candidate metastasis suppressor gene. | 44 |
| Tshz2 | −2.57 | −4.07 | May function as a tumor suppressor in breast and prostate cancer. | 45 |
Notes:
a
Relative up- or downregulated genes in consMydlow cells relative to control.
b
Relative up- or downregulated genes in indMydlow cells relative to control.
c
Select functions that have been attributed to the genes.