Table 2.
Comparison of visit 1 versus. visit 2 for three study groups
| Group 1 (n = 20) | Group 2a (n = 18) | Group 2b (n = 10)* | P value | |
|---|---|---|---|---|
| SBP (mmHg) | ||||
| Visit 1 | 138 (±13)* | 136 (±14)* | 177 (±12)∧ | <0.0001 |
| Visit 2 | 142 (±20)* | 152 (±19)*∧ | 171 (±27)∧ | 0.0036 |
| P value (SBP) | 0.53 | 0.0013 | 0.44 | |
| HR (bpm) | ||||
| Visit 1 | 104 (±23) | 109 (±27) | 126 (±28) | 0.094 |
| Visit 2 | 97 (±20) | 103 (±26) | 112 (±29) | 0.28 |
| P value (HR) | 0.094 | 0.14 | 0.18 | |
| % Sys HT Visit 2† | 20% | 28% | NA∧ | 0.709 |
| Chg BP# (mmHg) | +4 (±25)*∧ | +16 (±17)* | −6 (±25)∧ | 0.048 |
| UPC | ||||
| Visit 1 | 0.03 [0.01–0.33] | 0.07 [0.02–12.90] | Insufficient data | 0.042 |
| Visit 2 | 0.03 [0.01–0.41] | 0.06 [0.01–19.23] | Insufficient data | 0.014 |
| P value (UPC) | 0.53 | 0.51 | NA | |
| %Abn UPC | ||||
| Visit 1 | 0% | 11% | NA | 0.22 |
| Visit 2 | 0% | 22% | NA | 0.042 |
| P value (Abn UPC) | NA | 0.66 | NA | |
*n = 7 for the UPC data for Group 2b at visit 1. Three dogs were excluded from this analysis. See text for further information. ∧not analyzed, all dogs in category HT by design, †percent of dogs normotensive at previous visit that had SBP ≥ 160 mmHg at visit 2, #Mean (SD) difference in SBP between visit 1 and visit 2. SBP, systolic blood pressure; HR, heart rate; UPC, urine protein:creatinine ratio; NS, no significant difference (significance defined as P ≤ 0.05); NA, not applicable. Parametric data are expressed as mean (±SD); nonparametric data are expressed as median [range]. Groups with differing superscripts are significantly different at the P value indicated. HT, percentage of dogs with systemic hypertension: ≥160 mmHg; Abn UPC: UPC ≥ 0.5.