Table 2.
Change in total and subscale HRQoL scores between baseline and Week 56, by treatment arm, for IWQOL‐Lite and SF‐36
| Summary/subscale score | Liraglutide 3.0 mg | Placebo | ||||||
|---|---|---|---|---|---|---|---|---|
| n | Baseline score (LS mean ± SD) | Change from baseline score (LS mean ± SE) | Proportion of participants having maximum score at baseline/Week 56 (%) | n | Baseline score (LS mean) | Change from baseline score (LS mean ± SE) | Proportion of participants having maximum score at baseline/Week 56 (%) | |
| IWQOL‐Lite total | 1891 | 73.13 ± 18.01 | 10.66 ± 0.25 | 1.1/8.1 | 890 | 72.49 ± 17.86 | 7.54 ± 0.37 | 1.0/3.9 |
| Physical function | 1891 | 69.39 ± 21.65 | 13.36 ± 0.31 | 3.2/15.2 | 891 | 69.04 ± 21.98 | 8.55 ± 0.46 | 2.6/10.4 |
| Self‐esteem | 1893 | 61.12 ± 25.90 | 13.88 ± 0.41 | 6.1/20.3 | 891 | 58.99 ± 26.00 | 10.64 ± 0.59 | 5.3/15.0 |
| Sexual life | 1853 | 77.48 ± 26.45 | 8.51 ± 0.40 | 38.1/54.5 | 877 | 77.63 ± 26.20 | 6.03 ± 0.58 | 38.0/51.6 |
| Public distress | 1893 | 83.96 ± 20.59 | 6.03 ± 0.28 | 38.3/55.2 | 891 | 83.58 ± 20.45 | 4.44 ± 0.41 | 37.3/51.3 |
| Work | 1890 | 86.78 ± 18.43 | 5.56 ± 0.27 | 46.7/64.7 | 889 | 86.73 ± 18.57 | 4.51 ± 0.40 | 45.8/62.6 |
| SF‐36 PCS | 1690 | 48.25 ± 8.35 | 3.66 ± 0.15 | 0.0/0.0 | 799 | 47.67 ± 8.70 | 1.93 ± 0.21 | 0.0/0.0 |
| SF‐36 MCS | 1690 | 53.84 ± 8.08 | 0.14 ± 0.17 | 0.0/0.0 | 799 | 53.94 ± 7.93 | −0.76 ± 0.25 | 0.0/0.0 |
| Physical functioning | 1689 | 47.89 ± 8.47 | 3.64 ± 0.15 | 15.0/32.8 | 799 | 47.53 ± 8.76 | 2.08 ± 0.22 | 12.7/25.2 |
| Role physical | 1690 | 50.00 ± 8.25 | 2.76 ± 0.16 | 39.1/57.0 | 799 | 49.59 ± 8.64 | 1.29 ± 0.23 | 38.1/49.8 |
| Bodily Pain | 1690 | 50.80 ± 9.72 | 1.86 ± 0.21 | 27.6/35.7 | 799 | 50.33 ± 9.81 | −0.02 ± 0.30 | 25.0/27.7 |
| General health | 1689 | 49.50 ± 8.76 | 3.30 ± 0.16 | 2.9/6.1 | 797 | 49.03 ± 8.70 | 1.43 ± 0.23 | 1.8/4.2 |
| Vitality | 1689 | 52.57 ± 8.88 | 2.43 ± 0.19 | 1.9/5.0 | 799 | 52.12 ± 8.69 | 1.10 ± 0.27 | 1.9/2.9 |
| Social functioning | 1689 | 51.89 ± 7.80 | 1.11 ± 0.16 | 61.5/68.9 | 799 | 51.91 ± 7.83 | 0.09 ± 0.24 | 61.1/64.5 |
| Role emotional | 1690 | 51.53 ± 7.82 | 0.17 ± 0.16 | 64.6/69.2 | 799 | 51.99 ± 7.16 | −0.35 ± 0.24 | 66.5/66.5 |
| Mental health | 1689 | 53.40 ± 8.29 | 0.76 ± 0.18 | 8.1/11.4 | 799 | 53.00 ± 8.19 | −0.45 ± 0.27 | 7.0/8.6 |
IWQOL‐Lite, Impact of Weight on Quality of Life‐Lite; MCS, mental component summary; PCS, physical component summary; SD, standard deviation; SE, standard error; SF‐36, Short‐Form 36; LS, least square.