Table 1.
Subject characteristics and dialysis prescriptions at follow-up
| Characteristic | Intervention Group | P Value | |
|---|---|---|---|
| Standard Kt/Vurea, n=643 | High Kt/Vurea, n=638 | ||
| Characteristic | |||
| Age, yr | 58±14 | 58±14 | NS |
| Women, % | 57 | 57 | NS |
| Black race, % | 64 | 62 | NS |
| Diabetes, % | 46 | 45 | NS |
| On dialysis, yr | 3.8±4.1 | 3.8±4.2 | NS |
| Residual urea clearance >0, % | 27 | 29 | NS |
| Weight after dialysis, kg | 71±16 | 69±15 | 0.07 |
| Serum albumin, g/dl | 3.6±0.4 | 3.6±0.4 | NS |
| nPCR, g/kg per d | 1.00±0.26 | 1.07±0.31 | <0.001 |
| spKt/Vurea | 1.32±0.31 | 1.73±0.44 | <0.001 |
| Dialysis prescription | |||
| Treatment time, min | 193±62 | 221±63 | <0.001 |
| Blood flow rate, ml/min | 311±60 | 376±41 | <0.001 |
| Dialysate flow rate, ml/min | 639±134 | 708±116 | <0.001 |
| KoAurea, ml/min | 547±55 | 563±42 | <0.001 |
| Ultrafiltration, L | 2.9±1.3 | 3.0±1.3 | NS |
Values for blood flow rate are adjusted from the blood pump meter values as described by Depner et al.43 Values for KoAurea are estimated as described in Concise Methods. P values were estimated by t or rank sum test for continuous variables and proportion ratio test for categorical variables without correction for multiple comparisons (NS is P>0.05). Normality of continuous variables was tested using the Shapiro–Wilk test. The P values for continuous variables were similar, except for postdialysis weight P value was P=0.02 by t test and P=0.07 by rank sum test.