Table 1.
Name | FSME-Immun§ | Encepur | TBE Moscow | EnceVir |
---|---|---|---|---|
Virus subtype | European | European | Far Eastern | Far Eastern |
Manufacturer | Pfizer, Austria | Novartis Vaccines, Germany | Chumakov Institute, Moscow, Russia | Microgen, Tomsk, Russia |
Year of approval | 1976 | 1994 | 1982 | 2001 |
Standard regimen (3 doses) | ||||
Dose 1 | Day 0 | Day 0 | Day 0 | Day 0 |
Dose 2 | Month 1–3 | Month 1–3 | Month 1–7 | Month 5–7 |
Dose 3 | Month 9–12 | Month 9–12 | Month 12 | Month 16–18 |
Rapid/accelerated regimen | ||||
Dose 1 | Day 0 | Day 0 | N/A | Day 0 |
Dose 2 | Day 14 | Day 7 | Day 21–35** | |
Dose 3 | Month 5–12 | Day 21 | Day 42–70** | |
Dose 4 | N/A | Month 12–18 | Month 5–12 | |
Pediatric use | ||||
Age range | 1–15 years | 1–12 years | From 3 y of age | From 3 y of age |
Pediatric formulation | FSME-Immun Junior (half of adult dose) | Encepur-Children (half of adult dose) | Same dose as adultss | N/A, recommended to half the adult dose |
Ongoing protection | ||||
Booster | Every 5 years | Every 5 years | Every 3 years | Every 3 years |
Booster in >60 y of age | Every 3 years | Every 3 years | Every 3 years | Every 3 years |
Availability | EU, Russia, Canada | EU, Russia | Russia, Ukraine, Kazakhstan, Belarus | Russia, Ukraine, Kazakhstan, Belarus |
Marketed as TicoVac and TicoVac Junior in the UK and Canada;
from 6 months of age in high risk areas;
double dose. Adapted from Kollaritsch et al. 2011.5