Table 1.
Comparison of individual and neighborhood characteristics for the 3 cohorts (vaccinated children and unvaccinated children from pre- and post-universal vaccination periods).
| Vaccinateda cohort from post-universal vaccination period (n = 5,033) |
Unvaccinated cohort from pre-universal vaccination period (n = 6,436) | pb | Unvaccinated cohort from post-universal vaccination period (n = 1,239) | pb | |
|---|---|---|---|---|---|
| Sex, n (%) | |||||
| Male | 2,588 (51.4) | 3,304 (51.3) | 0.927 | 646 (52.1) | 0.655 |
| Follow-up time, median [IR], months | 16 [9–23] | 16 [9–23] | <0.001 | 20 [11–29] | <0.001 |
| Maternal age at birth, mean ± SD, years | 28.7 ± 5.0 | 28.3 ± 5.0 | <0.001 | 29.3 ± 4.8 | <0.001 |
| Prematurity, n (%) | 405 (8.0) | 475 (7.4) | 0.183 | 117 (9.4) | 0.111 |
| Low birth weight, n (%) | 311 (6.2) | 384 (6.0) | 0.636 | 101 (8.2) | 0.012 |
| Place of residence at birth, n (%) | |||||
| East Central (Sherbrooke) West |
1,031 (20.5) 3,058 (60.8) 944 (18.8) |
1,390 (21.6) 3,750 (58.3) 1,296 (20.1) |
0.025 | 303 (24.5) 702 (56.7) 234 (18.9) |
0.006 |
| Low-income family rate, n (%) T1 and T2 (low and middle) T3 (high) |
3,320 (67.5) 1,597 (32.5) |
4,296 (67.2) 2,100 (32.8) |
0.691 | 807 (66.1) 414 (33.9) |
0.342 |
| Unemployment rate, n (%) T1 and T2 (low and middle) |
3,317 (67.2) | 4,236 (65.9) | 0.151 | 819 (67.0) | 0.869 |
| T3 (high) | 1,618 (32.8) | 2,189 (34.1) | 404 (33.0) | ||
| Single mothers rate, n (%) | |||||
| T1 and T2 (low and middle) T3 (high) |
3,338 (67.5) 1,608 (32.5) |
4,224 (65.6) 2,212 (34.4) |
0.037 | 827 (67.5) 399 (32.5) |
0.982 |
| Proportion of mothers without | |||||
| high school diploma, n (%) | |||||
| T1 and T2 (low and middle) T3 (high) |
3,380 (68.3) 1,566 (31.7) |
4,227 (65.7) 2,209 (34.3) |
0.003 | 824 (67.2) 402 (32.8) |
0.448 |
a
Vaccinated children received ≥1 dose of RVV before June 1st 2014.
b
For comparison of vaccinated cohort and respective unvaccinated cohorts.
IR indicates interquartile range.
SD indicates standard deviation.