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. 2016 Oct 28;11(10):e0165372. doi: 10.1371/journal.pone.0165372

Fig 3. Securinine induced apoptosis in HeLa cells.

Fig 3

The distribution of the apoptotic cells was determined by flow cytometry. The cells were incubated with 0.5% DMSO (A) and securinine at concentrations of 1.0 (B), 5.0, 10.0 (C), 15.0, 20.0 (D), 30.0 (E) and 50.0 μg/ml (F) for 24 h. The percentage of early and late apoptotic cells (apoptosis rate) was estimated in comparison to the DMSO control (G). Each sample was run at least in triplicate. Error bars represent standard deviations. Significant differences relative to the control are marked with an “*” (p<0.05).