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The cells nuclei were stained with Hoechst 33342 dye after treating the cells with 0.5% DMSO (A) and securinine at concentrations of 1.0 (B), 5.0 (C), 10.0 (D), 15.0 (E), 20.0 (F), 30.0 (G) and 50.0 μg/ml (H). The cells exposed to securinine showed condensed chromatin in comparison to the control sample (DMSO). Arrows represent nuclear changes in the apoptotic cells.
