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. 2016 Oct 28;11(10):e0165372. doi: 10.1371/journal.pone.0165372

Fig 6. Securinine treatment increased activity of caspase-3/7 in HeLa cells.

Fig 6

The activity of the caspase was measured after 24 h of incubating the cells with 0.5% DMSO (A) and securinine at concentrations of 1.0 (B), 5.0, 10.0 (C), 15.0, 20.0 (D), 30.0 (E) and 50.0 μg/ml (F). Caspase-3/7 activation is represented as the percentage of the apoptotic cells (apoptosis rate) which was determined in comparison to the control (DMSO) (G). Each sample was run at least in triplicate. Error bars represent standard deviations. Significant differences relative to the control are marked with an “*” (p<0.05).