Skip to main content
. 2016 Oct 28;11(10):e0165372. doi: 10.1371/journal.pone.0165372

Fig 7. Securinine-induced changes in transmembrane mitochondrial potential in HeLa cells.

Fig 7

The cells were exposed to 0.5% DMSO (A) and securinine at concentrations of 1.0, 5.0, 10.0 (B), 15.0, 20.0(C, D), 30.0 (E, F) and 50.0 μg/ml (G, H). The cells were treated for 5 h (A, B, C, E, G) and 8 h (A, B, D, F, H) and the extent of mitochondrial cell depolarization was determined in comparison to the DMSO control (I). Each sample was run at least in triplicate. Error bars represent standard deviations. Significant differences relative to the control are marked with an “*” (p<0.05).