Table 1.
Variable | Acetaminophen (N = 150) | Ibuprofen (N = 150) |
---|---|---|
Demographic characteristic | ||
Age — mo | 40.3±12.9 | 39.4±13.6 |
Male sex — no. (%) | 86 (57) | 93 (62) |
Race or ethnic group — no. (%)† | ||
White | 74 (49) | 74 (49) |
Black | 47 (31) | 50 (33) |
Hispanic or Latino | 35 (23) | 37 (25) |
Age at onset of asthma — mo | 13.1±9.4 | 13.1±10.9 |
Parent with history of asthma — no. (%) | 87 (58) | 91 (61) |
Asthma measure at time of randomization | ||
Oral glucocorticoid courses in the previous 6 months — no. | 1.01±1.06 | 1.15±1.04 |
Urgent care or emergency department visits in the previous year — no. | 3.13±2.45 | 2.96±2.29 |
Hospitalizations in the previous year — no. | 0.29±0.57 | 0.26±0.51 |
Percentage of asthma-control days‡ | 85.5±18.7 | 85.6±16.2 |
Albuterol inhalations per week — no. | 1.81±3.49 | 1.50±2.22 |
Use of inhaled glucocorticoids in the previous 12 months — no. of patients (%) | 92 (61) | 86 (57) |
Use of leukotriene receptor antagonist in the previous 12 months — no. of patients (%) | 22 (15) | 39 (26) |
Measure of atopy at time of randomization | ||
Median IgE (interquartile range) — kU/liter | 64 (19–176) | 70 (24–252) |
Median blood absolute eosinophil count (interquartile range) — cells/mm3 | 259.6 (172.5–524.8) | 248.4 (132.8–450.0) |
Positive aeroallergen test — no. of patients (%) | 64 (43) | 62 (41) |
Plus–minus values are means ±SD. There were no significant differences between the two treatment groups in the characteristics listed.
Race or ethnic group was self-reported.
Asthma-control days were defined as full calendar days without the use of rescue medications for asthma, daytime asthma symptoms, nocturnal asthma symptoms, and unscheduled health care visits for asthma.