Fig 2. Normal agonist-induced aggregation of isolated Pdlim7^-/- platelets.

Washed platelets from WT (black lines) and Pdlim7^-/- (red lines) mice were stimulated with the following agonists: (A) type I collagen, (B) CRP, (C) ADP, and (D) thrombin. Light transmission was recorded and plotted; arrows indicate 50% light transmission. Graphs represent the average maximum aggregation of Pdlim7^-/- platelets relative to normal platelets at a given agonist concentration. Typical aggregation traces of platelets pooled from 5 mice per genotype and representative of n = 6 individual experiments. Abbreviations: CRP: collagen related peptide (AYPGKF).