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. 2016 May 29;7(23):33571–33580. doi: 10.18632/oncotarget.9654

Table 2. Effects of TH-302 and ionizing radiation on TIC frequency.

Frequency lower Frequency upper Frequency
OCIP19
control 1:1,386 1:2,263 1:849
IR 1:18,932 1:35,427 1:10,117
TH-302 50mg 1:162 1:473 1:56
TH-302 150mg 1:1,639 1:3,600 1:746
TH-302+IR 50mg 1:4,463 1:9,860 1:2,020
TH-302+IR 150mg 1:32,225 1:57,178 1:18,162
OCIP23
control 1:46 1:67 1:31
IR 1:266 1:431 1:164
TH-302 50mg 1:107 1:287 1:40
TH-302 150mg 1:121 1:311 1:44
TH-302+IR 50mg 1:2,211 1:4,520 1:1,082
TH-302+IR 150mg 1:18,324 1:38,188 1:8,793
OCIP51
control 1:8 1:11 1:7
IR 1:2,014 1:3,368 1:1,204
TH-302 50mg 1:80 1:131 1:49
TH-302 150mg 1:1,743 1:3,160 1:962
TH-302+IR 50mg 1:9,873 1:17,236 1:5,655
TH-302+IR 150mg 1:7,581,431 1:17,535,190 1:3,277,872
OCIP83
control 1:1,579 1:3,299 1:756
IR 1:12,748 1:26,702 1:6,086
TH-302 50mg 1:810 1:1,589 1:413
TH-302 150mg 1:9,488 1:24,719 1:3,642
TH-302+IR 50mg 1:45,903 1:85,665 1:24,597
TH-302+IR 150mg 1:845,975 1:526,700 1:2,141,477