Table 5. PLCE1 rs2274223 and PTGER4 and PRKAA1 rs13361707 predict the risk of cardia cancer in populations with a hereditary background.
PLCE1 –PRKAA1 | CasesA N (%) | CasesB N (%) | Controls N (%) | CasesA vs. Controls | CasesA vs. CasesB | ||
---|---|---|---|---|---|---|---|
OR | P value | OR | P value | ||||
AA-AA | 7 (10.8%) | 11 (21.6%) | 18 (17.6%) | 1 (reference) | 1 (reference) | ||
AA-GA | 19 (29.2%) | 17 (33.3%) | 33 (32.3%) | 1.48 | 0.4582 | 1.76 | 0.3356 |
AG-AA | 6 (9.2%) | 2 (3.9%) | 7 (6.9%) | 2.20 | 0.2631 | 4.71 | 0.0892 |
AG-GA | 19 (29.2%) | 4 (7.8%) | 16 (15.7%) | 3.05 | 0.0428* | 7.46 | 0.0039† |
P < 0.05;
P < 0.01;
P < 0.001