Figure 3. Cephalexin increases persistent DNA damage in irradiated B16.SIY cells.

A. Representative images from neutral comet assay of irradiated B16.SIY cells. Cells were treated with 25 μM veliparib and 50 μM cephalexin. Drugs were administered 1 hour prior to IR. Comet assays were performed 24 hours post IR. B. Plots of comet tail moment and C. Percent tail DNA with ± SEM are shown. ***, p ≤ 0.001, Mann-Whitney test relative to 6 Gy.