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. 2016 Apr 25;7(23):33919–33933. doi: 10.18632/oncotarget.8984

Table 1. Radiosensitization of B16.SIY tumors by small molecule inhibitors of IRIF resolution.

Compound or generic name Brand name Growth delay Bioactivity Drug dosing Source of drug
Cephalexin Keflex +++ cephalosporin antibiotic 30 mg/kg twice daily by gavage MP Biomedicals
CGS15943 +++ adenosine receptor antagonist 3 mg/kg by gavage Tocris Bioscience
Clotrimazole Lotrimin +++ azole antifungal 100 mg/kg by gavage Alexis Biochemicals
Doxepin Sinequan ++ tricyclic antidepressant 5 mg/kg, IP NIH Clinical Collection
Fluoxetine Prozac +++ serotonin reuptake inhibitor 10 mg/kg by gavage Tocris Bioscience
Fluvoxamine Luvox + serotonin reuptake inhibitor 30 mg/kg by gavage NIH Clinical Collection
Ketotifen Alaway ++ antihistamine 30 mg/kg, SQ Enzo Life Sciences
Losartan Cozaar ++ angiotensin 2 receptor blocker 90 mg/kg by gavage Santa Cruz Biotechnology
Nisoldipine Sular ++ calcium channel blocker 60 mg/kg by gavage Toronto Research Chemicals
Pergolide Permax + dopamine receptor agonist 40 mg/kg by gavage Tocris Bioscience
Pitavastatin Livalo +++ statin 30 mg/kg by gavage Atamole
Quercetin ++ antioxidant flavonol 30 mg/kg by gavage Calbiochem
Resveratrol +++ antioxidant stilbenoid 20 mg/kg by gavage Santa Cruz Biotechnology
Rucaparib +++ PARP inhibitor 25 mg/kg twice daily by gavage AxonMedChem
Synephrine Oxedrine +++ adrenergic receptor agonist 3 mg/kg by gavage LKT Laboratories.
Terbinafine Lamisil ++ allylamine antifungal 100 mg/kg by gavage LKT Laboratories
Trazodone Depyrel +++ serotonin reuptake inhibitor 25 mg/kg, IP Toronto Research Chemicals
Trifluoperazine Stelazine ++ antidopaminergic antipsychotic 0.5 mg/kg, IP Alexis Biochemicals
Veliparib +++ PARP inhibitor 25 mg/kg twice daily by gavage ChemiTek