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SMMC-7721 cells (1 × 107) were injected into 5-week-old female Balb/c nude mice. After tumors grew to 50–100 mm3, mice were given QPB-15e (10 or 20 mg/kg every day). Solid tumors in QPB-15e-treated mice were smaller than in untreated mice (A–B) QPB-15e inhibited tumor growth as measured by tumor volume (C) QPB-15e did not inhibit body weight increase compared with the control group (D).
