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. 2016 Apr 30;7(23):34430–34441. doi: 10.18632/oncotarget.9119

Figure 4. Suppression of APE1 enables to inhibition of gastric cancer cells migration and renewal features.

Figure 4

(A) AGS and NCI-N87 cells treated with the concentration of AT101 (5 μM) and APE1 siRNA for observing migration determined by transwell assays with matrigel. (B) and (C) The statistical data was shown on the plot (t test; *, P < 0.05). (D) and (E) Several stem-cell like markers (CD133, Nanog and LC3 (lower band shown)) was detected in AGS and NCI-N87 cells with incubation of AT101 (0.5, 2.5, and 5 μM) for 48 hours by western blot.