Table 1. A list of primers for DUB screening.

Gene name	Direction	Primer sequence	Size of PCR product (bp)
USP1	Forward	5′-GGA CTG AAT AAT CTC GGC-3′	289
	Reverse	5′-GCT GAG TGG CAA GTT CAT-3′
USP2	Forward	5′-TCT TCG TCA GCT GGT GCT-3′	293
	Reverse	5′-ATA GGA GGA CGG GGT GTA-3′
USP3	Forward	5′-CCT TGG GCT TGT TTG ACT-3′	284
	Reverse	5′-TTA TGC CTG TCA GCT GTG-3′
USP4	Forward	5′-AAG CAC TGC AAA GTC GAG-3′	255
	Reverse	5′-TAG CAC CTG ACC CTG GTA-3′
USP5	Forward	5′-GTC CAC AAA GAC GAG TGC-3′	257
	Reverse	5′-CTA AGG TCA AAT CCG CCT-3′
USP6	Forward	5′-GTT GGA ATC AAC AGC AGC-3′	266
	Reverse	5′-TAT CTT CCG GGG TTT TTC A-3′
USP7	Forward	5′-GGG ATG GCA AAT GGT GTA-3′	300
	Reverse	5′-TCC TCT GCG ACT ATC TGC-3′
USP8	Forward	5′-ATT TCA AGC AAC AGC AGG A-3′	263
	Reverse	5′-GGG TTT TGT CTT TGC AAT C-3′
USP9X	Forward	5′-TAG GCT TCA AGG TTC CAG-3′	264
	Reverse	5′-CTG TGG CTG ATG AAG ACT-3′
USP9Y	Forward	5′-CTT ATG GAT GAG GCT GTG-3′	250
	Reverse	5′-CCA CTA GCC AAC CTT TTG-3′
USP10	Forward	5′-TTC AAG CAC ACT GAA CCC-3′	250
	Reverse	5′-TGG CAT GGC CAT TGA CCA-3′
USP11	Forward	5′-AAA GAT GGC ACT TGG CCC-3′	326
	Reverse	5′-CCA ACC TTG TTC TTG AAC A-3′
USP12	Forward	5′-AGT CTC CAA ATT CGC CTC-3′	261
	Reverse	5′-GTG GCT ATG CTA TGG AAG-3′
USP13	Forward	5′-GAG TCA GGA TTC CTC CAA-3′	259
	Reverse	5′-TTG GCC AAA TGA GGA TCC-3′
USP14	Forward	5′-GAT GAA CCT CCA ATG GTA T-3′	194
	Reverse	5′-GGC ACA GAA CCA ATA CAC-3′
USP15	Forward	5′-AAA CCT CGC TCC GGA AAG-3′	252
	Reverse	5′-CCC TGT TCA ACC ACC TTT-3′
USP16	Forward	5′-CAT GGG AAA GAA ACG GAC-3′	252
	Reverse	5′-CTC CTG AGA ATT CCT GCC-3′
USP17	Forward	5′-CAA GGA GAG CTC AAG AGA-3′	259
	Reverse	5′-AAG AGA GGT TTA GCA GGG-3′
USP18	Forward	5′-CCT GGA AGT GAA GTC GTG-3′	280
	Reverse	5′-CAA GGA GTT AAG GCA GCA-3′
USP19	Forward	5′-TGT GGG CTA CTG CAA CCA-3′	296
	Reverse	5′-GCT GAA TGG GGT CTC TCT-3′
USP20	Forward	5′-CCT ATT GCT GTG GCT GAT-3′	318
	Reverse	5′-GGC ATA GCC TCG GAG CAT-3′
USP21	Forward	5′-AGT GGG ATC CAA GCT ACC-3′	279
	Reverse	5′-CTC ACA GAC TTG GAA CGG-3′
USP22	Forward	5′-CAG CTT CAA GGT GGA CAA-3′	265
	Reverse	5′-AGA TGT AGT CCT GGC ACA-3′
USP24	Forward	5′-GGC TGG ATA ACT TTG AAC T-3′	209
	Reverse	5′-ACT TTG GAT GAA AGT CCT G-3′
USP25	Forward	5′-TAT CTA GAG CAG CCA TCA A-3′	230
	Reverse	5′-GCC TGG TTC TGG ATA AAG-3′
USP26	Forward	5′-GTC CAG ATG TGG AGT GCA-3′	240
	Reverse	5′-GCC GAA TAC TAC CTT GAG-3′
USP27	Forward	5′-CCA CTC TTG CCT TTC CTG-3′	347
	Reverse	5′-CCG ATC GTA AAG CTG GAG-3′
USP28	Forward	5′-CCC ACC TCT CAC AGT GAT-3′	314
	Reverse	5′-TAC ACA GAC ACT TTT CGG A-3′
USP29	Forward	5′-TTG GGA AAC ACC TGT TAC T-3′	288
	Reverse	5′-TTT CAG CTG GTC TAA ACA C-3′
USP30	Forward	5′-CAG CGC TTC CTG CGG AC-3′	266
	Reverse	5′-TCC CTG GAG TAC TGG GAG-3′
USP31	Forward	5′-ACT GGG TGA GCC GGC T-3′	268
	Reverse	5′-GAG CGC ATC TGC AGC TTA-3′
USP32	Forward	5′-GTC CCA GAT ACA CTC AGG-3′	194
	Reverse	5′-AAT GTG TGA CTC CAG CCA-3′
USP33	Forward	5′-GGA AGA GCA GCG AAG AG-3′	234
	Reverse	5′-CCC AAA CGT TCT GAG GCA-3′
USP34	Forward	5′-AAG ACA CAT CTG GAA GCG-3′	275
	Reverse	5′-CCA AAC TCC TGA AGC TGA-3′
USP35	Forward	5′-TGT TCG CAG TCA TCT CCT-3′	244
	Reverse	5′-TTC TTA ACA GCA GCC AGG-3′
USP36	Forward	5′-AAG GAC TCG GCT GAT GAT-3′	273
	Reverse	5′-GGG GAA AAG CAC TTT CTG-3′
USP37	Forward	5′-ACT GGA GGA ATT CCA AGG-3′	287
	Reverse	5′-TAA GAA AGC TGC CTG CTG-3′
USP38	Forward	5′-CCT TGT GCA GCA TAT TCC-3′	285
	Reverse	5′-AGA ACT GCA AGA GCA CCA-3′
USP39	Forward	5′-CAA GTA CTT TCA AGG CCG-3′	236
	Reverse	5′-TGG TAC CAT CAT ATG CCC-3′
USP40	Forward	5′-TGG AAT GGG GTG GAG GTT-3′	300
	Reverse	5′-GCT TCC ATT TCT GAC CCT-3′
USP41	Forward	5′-CCT TAC GCC AGT GAC TAT-3′	250
	Reverse	5′-CAA GGA GGT AAG GCA GCA-3′
USP42	Forward	5′-TAG CAA TGG CCT CTG GTA-3′	298
	Reverse	5′-TGG CGT GTC TTT CAA TGG-3′
USP43	Forward	5′-CAG AAG CGG AAC AGC ATC-3′	259
	Reverse	5′-TGC CTT CAT GCT AAT GCT T-3′
USP44	Forward	5′-ACC GAG TCC ATT TGG GCT-3′	278
	Reverse	5′-ACT TCA GGT CTC CAG TTG-3′
USP45	Forward	5′-CGG GTG AAA GAT CCA ACT-3′	264
	Reverse	5′-ACA CTT GAG GCA CAA CCA-3′
USP46	Forward	5′-GGA TGA GGG TAA AAA AGC T-3′	199
	Reverse	5′-CTT TCA CAG TGA ACG ACC-3′
USP47	Forward	5′-TGT TGA AAG CTC CGA GAC-3′	278
	Reverse	5′-CTG CTG TTG TG CAG TGA −3′
USP48	Forward	5′-CCG AAT TGC TTG GTT GGT −3′	300
	Reverse	5′-CAA GTA CTG GAG ATG CTC-3′
USP49	Forward	5′-GAT GCA AAC ATG TAG GGC-3′	256
	Reverse	5′-TCA TTG AGC ACG TAG TCC-3′
USP50	Forward	5′-GTG CTT CAT TGA CAT GGC-3′	258
	Reverse	5′-CTC ACT GCA GTC CTT CTT-3′
USP51	Forward	5′-ACC CCA GAG ACT AGG AAA-3′	243
	Reverse	5′-TTC TTT GGC AAT CTG TTC TA-3′
USP52	Forward	5′-TCT GGC AAG GTT TCC CTG-3′	187
	Reverse	5′-CAC GCA TCA TGC GCA AAT-3′
USP53	Forward	5′-GAT ATG ACA CAG ACA GCA G-3′	299
	Reverse	5′-AAG GGA ACT TCT GCT TCC-3′
USP54	Forward	5′-GGT AGT GTA CAA GGG ATG TT-3′	260
	Reverse	5′-GAG AGT GTC AGA TGG AAG C-3′
USP55	Forward	5′-GCA ACC TCA TGC AGT TCT-3′	240
	Reverse	5′-AAA CCT TGA CCA CGA CCT-3′
CYLD	Forward	5′-GCA ACC TCA TGC AGT TCT-3′	300
	Reverse	5′-AAA CCT TGA CCA CGA CCT-3′