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A. Upregulation of SIRT1 was observed in CRC tissue samples compared with that in adjacent CRN ones by qRT-PCR. B. Spearman correlation was performed to assess relationship between expression levels of SIRT1 and miR-199b (r=−0.5425). C. KISS1 expression was decreased in CRC tissues compared to that in CRN ones. **P<0.01.
