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. 2016 Apr 28;7(23):35188–35198. doi: 10.18632/oncotarget.9072

Figure 5. mir-101-3p-AMPK axis is a key regulator of tumor metabolism and inhibits proliferation in triple negative breast cancer in vitro.

Figure 5

A. MDA-MB-231 and MDA-MB-468 cells were transfected with control vector or AMPK-expression vector followed by scrambled oligonucleotide or mir-101-3p mimics. After transfection the level of glucose uptake was measured. B. MDA-MB-231 and MDA-MB-468 cells were transfected as described before. The level of lactate production was measured after transfection. C. MDA-MB-231 and MDA-MB-468 cells were transfected with control vector, AMPK-expression vector, control vector + scrambled oligonucleotide or AMPK-expression vector + mir-101-3p mimics respectively. The number of cells was counted. All of the data are shown as the means ± s.e.m. * P < 0.05, ** P < 0.01.