Table 1. Clinicopathological variables and MAPK expression in 112 breast cancer patients.

Characteristics	Total (n=112)	MAPK low (n=43)		MAPK high (n=69)		P value
		No.	%	No.	%
Age (years)						0.495
<50	67	24	35.8	43	64.2
>=50	45	19	42.2	26	57.8
Menopause						0.964
Yes	55	21	38.2	34	61.8
No	57	22	38.6	35	61.4
Tumor size (cm)						0.075
=<2	31	16	51.6	15	48.4
>2	81	27	33.3	54	66.7
LNMET						0.087
Yes	66	21	31.8	45	68.2
No	46	22	47.8	24	52.2
TNM stage						0.004*
I-II	59	30	50.8	29	49.2
III-IV	53	13	24.5	40	75.5
Local relapse						0.092
Yes	5	0	0	5	100.0
No	107	43	40.2	74	59.8
Distant metastasis						0.000*
Yes	29	3	10.3	26	89.7
No	83	40	48.2	43	51.8
ER status						0.313
Positive	84	30	35.7	54	64.3
Negative	28	13	46.4	15	53.6
PR status						0.035*
Positive	46	23	50.0	23	50.0
Negative	66	20	30.3	46	69.7
HER-2 status						0.127
Positive	21	5	23.8	16	76.2
Negative	91	38	41.8	53	58.2
P53 status						0.052
Positive	44	12	27.3	32	72.7
Negative	68	31	45.6	37	54.4
VEGF status						0.563
Positive	74	27	36.5	47	63.5
Negative	38	16	42.1	22	57.9
TNBC status						0.001*
TNBC	42	8	19.0	34	81.0
NON-TNBC	70	35	50.0	35	50.0
Ki67 status						0.520
Positive	59	21	35.6	38	0.644
Negative	53	22	41.5	31	58.5

^*means statistically significant (P < 0.05).

% means percentage within the row.

TNBC, triple-negative breast cancer, means ER(—), PR(—), HER-2(—).