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EGCG treatment increases A. RXRα protein levels, attenuates nuclear β-catenin levels and cyclin D1 protein levels, and B. increase cytosolic phospho-β-catenin and β-catenin in CIMP+ lines (HCT116, SW48), while a modest changes was observed (HT29) and little change in the CIMP- cell line (SW480). Total of 50 μg of nuclear and cytosolic protein was used in each blot.
