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. 2016 May 11;7(23):35369–35378. doi: 10.18632/oncotarget.9294

Table 1. The main features of enrolled studies.

Author Year Population Sample size Method Cut-off miRNA Survival analysis Source of HR Follow-up (month)
Luo 2015 China 88 qRT-PCR Median miR-26b OS, RFS Reported mean 74 (5.12-98.5)
Safari 2015 Iran 40 qRT-PCR Median miR-20a OS DE 100
miR-10a OS DE
Wang C 2015 China 138 qRT-PCR Median miR-335 OS, RFS Reported, DE Mean 71(23-117)
Wang Q 2015 China 114 qRT-PCR Median miR-145 OS Reported median 47(11-69)
He 2014 China 73 qRT-PCR ROC curve miR-107 OS, DFS DE median 68.4
miR-130a OS, DFS DE
Liang 2014 China 335 qRT-PCR X-tile algorithm miR-215 DFS Reported 60
Ma 2014 China 60 qRT-PCR ROC curve miR-205 OS Reported 60
Park 2014 Korea 45 qRT-PCR 2.5-fold miR-363-3p OS Reported 60
Wang 2014 China 54 qRT-PCR Median miR-31 OS Reported 60
Yang 2014 China 133 qRT-PCR Median miR-126 OS Reported 60
Luo 2013 China 60 qRT-PCR Mean miR-497 OS, DFS Reported, DE 60
Shen 2013 China 126 qRT-PCR Median miR-224 OS DE median 51.9
Huang 2012 China 44 qRT-PCR Mean miR-125b OS Reported mean 23.6 (2-70)
miR-100 OS Reported
miR-143 OS DE
miR-145 OS DE
miR-199a-5p OS DE

HR: hazard ratio; qRT-PCR: quantitative real-time polymerase chain reaction; OS: overall survival; RFS: recurrence-free survival; DFS: disease-free survival.