Table 1.
Baseline and clinical characteristics of 118 patients with severe COPD and acute infectious exacerbations
| Subjects | N=118 |
|---|---|
| Follow-up (days) | 1,003±306 |
| Age (years) | 69.5±8.2 |
| Current smoking | 13 (11) |
| Pack-years | 63.3±31.9 |
| Alcohol abuse >80 g/L | 3 (2.5) |
| Influenza vaccination | 105 (89) |
| Pneumococcus vaccination | 57 (48.3) |
| Body mass index (kg/m2) | 27.5±4.6 |
| FEV1 post-BD (L) | 0.97±0.3 |
| FEV1 post-BD (% predicted) | 34±11 |
| GOLD stage IV | 71 (60) |
| BODE score | 5.1±1.6 |
| Basal hypercapnia | 49 (41.5) |
| LTOT | 50 (42.4) |
| Charlson Comorbidity Index | 4.13±1.5 |
| Bronchiectasis | 56 (47.5) |
Notes: Data are presented as mean ± SD or n (%), unless otherwise stated. Hypercapnia defined as PaCO2 >5.9 Kpa.
Abbreviations: BODE, Body-mass index, airflow Obstruction, Dyspnea, and Exercise index; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 second; GOLD, Global Initiative for Chronic Obstructive Lung Disease; LTOT, long-term oxygen therapy; m, mean; post-BD, post bronchodilator; SD, standard deviation.