Table 3.
Markers of exacerbation severity (N=380)
| Reference values | Community-managed, n=227 | Hospital admitted, n=153 | P-value* | |
|---|---|---|---|---|
| CRP | <5 mg/L | 37.3 (12.8–82.7) | 67.4 (27.0–189.0) | <0.0001 |
| WBC count | 4,000–11,000 | 9,900 (7,860–11,460) | 10,030 (8,500–14,002) | 0.001 |
| RR | 12–16 breath/min | 24 (20–28) | 26 (24–30) | 0.002 |
| SaO2 | 96%–100% | 94 (92–95) | 89 (85–92) | <0.0001 |
| PaO2+ | 10.6–13.3 KPa | 7.9 (7.3–8.6) | 7.0 (6.2–7.6) | 0.002 |
| PaCO2+ | 4.6–5.9 KPa | 5.7 (5.2–6.6) | 6.2 (5.4–7.5) | 0.001 |
| pH+ | 7.35–7.45 | 7.42 (7.40–7.44) | 7.41 (7.39–7.44) | 0.443 |
Notes:
*
Univariate generalized estimating equation.
+
Only obtained in 197 episodes. Data presented as median (interquartile range).
Abbreviations: CRP, C-reactive protein; IQR, interquartile range; min, minutes; RR, respiratory rate; WBC, white blood cell.