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. 2016 Oct 21;9:6511–6518. doi: 10.2147/OTT.S116629

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© 2016 Chen et al. This work is published and licensed by Dove Medical Press Limited

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Effects of the combination of irradiation with CpG ODN 7909 on regulation of gene expression in H460 cells. H460 cells treated with CpG ODN 7909 alone or in combination with irradiation were subjected to qRT-PCR analysis of mRNA levels. All experiments were repeated three times. (A) PD-L1 level; (B) TLR9 level; (C) p65 level. *P<0.05 and **P<0.01 compared to the control.

Abbreviations: CpG ODN, CpG oligodeoxynucleotides; PD-L1, programmed death-ligand 1; TLR9, toll-like receptor 9; qRT-PCR, quantitative reverse transcriptase-polymerase chain reaction; IR, irradiation.