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. 2016 Oct 21;9:6511–6518. doi: 10.2147/OTT.S116629

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© 2016 Chen et al. This work is published and licensed by Dove Medical Press Limited

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Effects of p65 knockdown on regulation of PD-L1 expression. H460 cells were treated with CpG ODN 7909 alone or in combination with ionizing radiation and then transfected with p65 siRNA for 48 h and subjected to qRT-PCR analysis of PDL-1 levels. This graph represents PD-L1 level after transfection. *P<0.05 compared to the control.

Abbreviations: CpG ODN, CpG oligodeoxynucleotides; PD-L1, programmed death-ligand 1; h, hours; qRT-PCR, quantitative reverse transcriptase-polymerase chain reaction; IR, irradiation.