Figure 1.

Effects of IT administration of quinpirole and sulpiride on the response to noxious heat (A) and mechanical stimuli (B).

Notes: The plantar incision markedly reduced both the heat withdrawal latency (A) and the mechanical withdrawal threshold (B), indicating successful establishment of a decreased postoperative nociceptive threshold. (a) Before plantar incision and (b) IT administration. Between-group statistical comparisons were performed using one-way analysis of variance followed by Bonferroni’s post hoc test. Data are expressed as the means ± standard deviation (n=10, *P<0.05 vs saline, ^#P<0.05 vs sulpiride).

Abbreviation: IT, intrathecal; min, minutes, s, seconds.