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. 2016 Apr 7;4:29–39. doi: 10.2147/HP.S83540

Table 1.

Characteristics of wild-type and Epo-TAgh male mice in normoxic conditions

References Wild-type mice Epo-TAgh mice
Hemoglobin (g·dL−1)b Macarlupu et al81 17.1±0.3 6.9±0.3a
Hematocrit (%)b Macarlupu et al81 54.2±0.8 24.0±1.6a
Cardiac characteristics Heart rate (bpm)c El Hasnaoui-Saadani et al20 500±27 548±46
Stroke volume (μL·g−1)c El Hasnaoui-Saadani et al20 1.9±0.19 3.2±0.68a
Cardiac output (mL·min−1·g−1)c El Hasnaoui-Saadani et al20 0.94±0.14 1.76±0.43a
Systolic blood pressure (mmHg)c El Hasnaoui-Saadani et al20 96.7±8.5 94.2±5.8
Right ventricular weight (mg)b Macarlupu et al82 23±1 33±2a
Left ventricular and septum weight (mg)b Macarlupu et al82 80±2 113±3a
Fulton ratiob Macarlupu et al82 0.288±0.013 0.297±0.010a
Ventilatory parameters Minute ventilation (mL·min−1·g−1)c Voituron et al90 2.26±0.48 2.17±0.53
Respiratory frequency (c·min−1)c Voituron et al90 261±34 284±54
Tidal volume (μL·g−1)c Voituron et al90 8.63±1.26 7.62±1.09
Resting oxygen consumption (mL·min−1·kg−1)b Macarlupu et al81 93.3±4.7 96.8±6.5
Maximal oxygen consumption (mL·min−1·kg−1)b Macarlupu et al81 270.7±22.0 210.2±12.3a

Note:

a

Indicates significant difference between wild-type and Epo-TAgh mice.

b

Data presented as mean ± SEM.

c

Data presented as mean ± SD.

Abbreviations: Epo, erythropoietin; Epo-TAgh mice, Epo-deficient mice; SD, standard deviation; SEM, standard error of the mean.