Table 1.

Summary of the reported CML cases presenting with a bilineal extramedullary disease with bone marrow in chronic phase.

No.	Age/sex	BM at diagnosis		Extramedullary presentation of blastic crisis at diagnosis				Treatment	Outcome	Ref.
		Cytogenetic /FISH	RT-PCR	Biopsy site	Bilineal immunophenotype (positive antigen)	Cytogenetic /FISH	RT-PCR
1	14 /M	Ph	P210 BCR/ABL1	Lymph node	T-lymphoid/ myeloid (Blasts: CD3, TdT. Adjacent tissue: MPO, CD15, lysozyme)	Ph	Not done	Mitoxantrone, Cytarabine, Dasatanib. Allo-HSCT	Alive 0.8 year	[7]
2	14 /M	Ph	Not done	Lymph node	T-lymphoid/ myeloid (MPO, CD13, CD33, CD3, CD7)	Not done	Not done	Prednisolone, Vindesine, Daunorubicin, L-asparaginase. Per MCP 841 protocol	Dead 0.1 year	[8]
3	44 /F	Ph	P190 BCR/ABL1	Lymph node	T-lymphoid/ myeloid (MPO, CD5, CD7, CD13, CD33, CD34, HLA-DR)	Ph	P190 BCR/ABL1	Hydroxyurea	Not available	[13]
4	47 /M	Ph	Not done	Lymph node	T-lymphoid/ myeloid (CD5, CD7, CD33)	Ph	Not done	Etoposide	Dead 2.8 years	[15]