Figure 3. Impact of cystic fibrosis (CF) sputum biochemical composition on microstructure.

The correlations of log base 10 of the median MSD per μm² at time τ = 1 s (median log₁₀[MSD_1s]) of 100-nm MIP measured in sputum samples from 18 CF patients versus (A) percent solids, (B) mucin, (C) DNA, and (D) cystine (disulfide bond) content of each sputum sample. R² values were determined based on a linear regression analysis, and the correlations were considered statistically significant when P < 0.05.