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Mevalonate pathway and intermediates necessary for the posttranslational modification of Ras, Rho, and insulin-like growth factor I (IGF-I) receptor. T3, tocotrienol; HMG-CoA, 3-hydroxy-3-methylglutaryl-coenzyme A. Arrows and perpendicular lines indicate activation/induction and inhibition/suppression, respectively.
